Article
Interleukin-18 gene promoter--607 A/C polymorphism and the risk of immune thrombocytopenia.
Autoimmunity - 1 Nov 2014
Zhao Haifeng, Zhang Yizhuo, Xiao Gangfeng, Wu Ningning, Xu Jianfen, Fang Zhi
Abstract excerpt
Interleukin-18 (IL-18) is a T helper 1 cytokine, which is postulated to play a role in immune thrombocytopenia (ITP). The aim of this study was to determine whether IL-18 promoter gene -607 A/C polymorphism was associated with ITP. Three-hundred and fifty-four Chinese ITP patients and 300 Chinese healthy individuals were enrolled. Genomic DNA was extracted from the peripheral blood. Polymerase chain...
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