Article
New Targets in Atherosclerosis: Vascular Smooth Muscle Cell Plasticity and Macrophage Polarity.
Clinical therapeutics - 1 Nov 2023
Hutton Michael, Frazer Madeleine, Lin Alexander, Patel Sanjay, Misra Ashish
Abstract excerpt
PURPOSE: Despite an increase in treatment options, and substantial reductions in cardiovascular mortality over the past half-century, atherosclerosis remains the most prevalent cause of premature mortality worldwide. The development of innovative new therapies is crucial to further minimize atherosclerosis-related deaths. The diverse array of cell phenotypes derived from vascular smooth muscle cells (SMCs) and...
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