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Article

The eco-evolutionary dynamics of acute myeloid leukemia: From clonal games to clinical intervention.

Cancer treatment and research communications - 1 Jan 2026

Ye Chunmei, Fu Shuying, Li Juan, Xue Jiayin, Li Jun

Abstract excerpt

Acute myeloid leukemia (AML) is a hematologic malignancy characterized by high clonal heterogeneity, whose initiation and progression are driven by a complex process of clonal evolution. Integrating recent research advances, this review summarizes the multidimensional features of clonal evolution in AML, including the origin and heterogeneity of clones, the interaction between clones and the bone marrow...

Topics

Humans
Leukemia, Myeloid, Acute
Clonal Evolution
Tumor Microenvironment
Mutation
Prognosis

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 42542075
DOI: 10.1016/j.ctarc.2026.101349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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