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Article

Identification and validation of SERPINE1 as a prognostic and immunological biomarker in pan-cancer and in ccRCC

23 Aug 2023

Abstract excerpt

Background: SERPINE1 , a serine protease inhibitor involved in the regulation of the plasminogen activation system, was recently identified as a cancer-related gene. However, its clinical significance and potential mechanisms in pan-cancer remain obscure. Methods: In pan-cancer multi-omics data from public datasets, including The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx), and online web...

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PMID: 37680718
DOI: 10.3389/fphar.2023.1213891

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