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Article

Integrative genomic analysis identifies that SERPINA6-rs1998056 regulated by FOXA/ERα is associated with female hepatocellular carcinoma.

PloS one - 1 Jan 2014

Shen Na, Gong Jing, Wang Ying, Tian Jing, Qian Jiaming, Zou Li, Chen Wei, Zhu Beibei, Lu Xinghua, Zhong Rong, Guo Anyuan, Wang Li, Miao Xiaoping

Abstract excerpt

The human forkhead box A1 (FOXA1) and A2 (FOXA2) transcription factors have been found to control estrogen and androgen signaling through co-regulating target genes with sex hormone receptors. Here we used an integrative strategy to examine the hypothesis that genetic variants at FOXA1/2 binding...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 25198130
DOI: 10.1371/journal.pone.0107246
PMCID: PMC4157870

Genes

SERPINA6
FOXA1
FOXA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25198130-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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