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Bacterial Persistence Modulates the Speed, Magnitude, and Onset of Antibiotic Resistance Evolution.

Molecular biology and evolution - 1 Aug 2026

Boccarella Giorgio, Ruelens Philip, Berríos-Caro Ernesto, Van den Bergh Bram, Cool Lloyd, Michiels Jan, van den Berg Pieter

Abstract excerpt

Bacterial persistence, a phenomenon where a subpopulation of cells can exhibit increased survival to antibiotic stress, allows part of the population to withstand antibiotic treatment. This can have far-reaching implications for the evolution of antibiotic resistance, yet its evolutionary consequences remain insufficiently understood. Here, using a combination of evolutionary modeling and experimental evolution...

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Identifiers

PMID: 42483960
DOI: 10.1093/molbev/msag180
PMCID: PMC13475807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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