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Article

Ecology and evolution of antibiotic persistence.

Trends in microbiology - 1 May 2022

Verstraete L, Van den Bergh B, Verstraeten N, Michiels J

Abstract excerpt

Bacteria have at their disposal a battery of strategies to withstand antibiotic stress. Among these, resistance is a well-known mechanism, yet bacteria can also survive antibiotic attack by adopting a tolerant phenotype. In the case of persistence, only a small fraction within an isogenic population switches to this antibiotic-tolerant state. Persistence depends on the ecological niche and the genetic background...

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PMID: 34753652
DOI: 10.1016/j.tim.2021.10.001

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