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Article

Bacterial persistence: a model of survival in changing environments.

Genetics - 1 Apr 2005

Kussell Edo, Kishony Roy, Balaban Nathalie Q, Leibler Stanislas

Abstract excerpt

The persistence phenotype is an epigenetic trait exhibited by a subpopulation of bacteria, characterized by slow growth coupled with an ability to survive antibiotic treatment. The phenotype is acquired via a spontaneous, reversible switch between normal and persister cells. These observations suggest that clonal bacterial populations may use persister cells, whose slow division rate under growth conditions leads...

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Identifiers

PMID: 15687275
DOI: 10.1534/genetics.104.035352
PMCID: PMC1449587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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