Antibiotic Tolerance Indicative of Persistence Is Pervasive among Clinical Streptococcus pneumoniae Isolates and Shows Strong Condition Dependence.

doi:10.1128/spectrum.02701-22

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Article

Antibiotic Tolerance Indicative of Persistence Is Pervasive among Clinical Streptococcus pneumoniae Isolates and Shows Strong Condition Dependence.

Microbiology spectrum - 21 Dec 2022

Geerts Nele, De Vooght Linda, Passaris Ioannis, Delputte Peter, Van den Bergh Bram, Cos Paul

Abstract excerpt

Streptococcus pneumoniae is an important human pathogen, being one of the most common causes of community-acquired pneumonia and otitis media. Antibiotic resistance in S. pneumoniae is an emerging problem, as it depletes our arsenal of effective drugs. In addition, persistence also contributes to the antibiotic crisis in many other pathogens, yet for S. pneumoniae, little is known about antibiotic-tolerant...

Topics

Humans
Anti-Bacterial Agents
Streptococcus pneumoniae
Bacteria
Drug Resistance, Microbial
Phenotype

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Identifiers

PMID: 36374111
DOI: 10.1128/spectrum.02701-22
PMCID: PMC9769776

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