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Article

Activation of human bitter taste receptor (TAS2R) subtypes and TAS2R14 genotypes by Bacillus amyloliquefaciens exopolysaccharides.

Cell calcium - 1 Sept 2026

Sung Wei-Wen, Lin Tse-Hsuan, Tsai Hui-Hsin, Cheng Hsueh-Ling

Abstract excerpt

Bacillus amyloliquefaciens amy-1 is recognized as a probiotic for animals, and its exopolysaccharides (EPS) can lower blood sugar by activating specific human bitter-taste receptor type 2 (TAS2R) subtypes, particularly TAS2R14 and TAS2R38. Humans have 26 TAS2R subtypes, with some exhibiting different activities depending on genotype. However, differences in activity among TAS2R14 genotypes remain poorly studied....

Read the complete abstract on PubMed

Topics

Humans
Receptors, G-Protein-Coupled
Taste Receptors, Type 2
Polysaccharides, Bacterial
HEK293 Cells
Bacillus amyloliquefaciens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genotype

Calcium

Source

Identifiers

PMID: 42480453
DOI: 10.1016/j.ceca.2026.103170

Genes

TAS2R14
TAS2R38
TAS2R7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 15 Oct 2026.

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