Article

High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus

2023-08-16

Abstract excerpt

Genome-wide association studies implicate multiple loci in risk for systemic lupus erythematosus (SLE), but few contain exonic variants, rendering systematic identification of non-coding variants essential to decoding SLE genetics. We utilized SNP-seq and bioinformatic enrichment to interrogate 2180 single-nucleotide polymorphisms (SNPs) from 87 SLE risk loci for potential binding of transcription factors and rela...

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Literature Corpus work: 97bc9d49-e3b1-59b7-a2de-5f1679260d97
DOI: 10.1101/2023.08.16.553538

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