Article

Antibiotic heteroresistance generated by multi-copy plasmids

2022-08-24

Abstract excerpt

<h4>ABSTRACT</h4> Heteroresistance – in which a clonal bacterial population contains a cell subpopulation with higher resistance to antibiotics than the main population – is a growing clinical problem that complicates susceptibility determination and threatens therapeutic success. Despite the high prevalence of heteroresistance in clinical settings, the underlying genetic mechanisms that stably maintain heterogen...

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Literature Corpus work: 0c70e22c-90f7-568b-8da3-9307081c9eac
DOI: 10.1101/2022.08.24.505173

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