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Heteroresistance to colistin in wild-type Klebsiella pneumoniae isolates from clinical origin

14 Nov 2023

Abstract excerpt

ABSTRACT Heteroresistance to colistin can be defined as the presence of resistant subpopulations in an isolate that is susceptible to colistin. The aim of this work was to study heteroresistance in 10 wild-type Klebsiella pneumoniae isolates of clinical origin, to determine the importance of persisters variants and stable mutants in heteroresistance, and to describe genomic changes observed in mutants obtained in...

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PMID: 37962370
DOI: 10.1128/spectrum.02238-23

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