Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intrinsic Capacity, Polygenic Risk Score, and Risk of Glaucoma.

Translational vision science & technology - 1 Jun 2026

Kai Jia-Yan, Gong Shi-Yi, Hu Yu-Hui, Dong Xing-Xuan, Li Dan-Lin, Ke Chaofu, Pan Chen-Wei

Abstract excerpt

Purpose: The purpose of this study was to investigate the prospective association between intrinsic capacity (IC) and the risk of incident glaucoma. Methods: We performed prospective cohort analyses among 397,881 UK Biobank participants. An IC deficit composite score was constructed based on six IC components. Cox proportional hazards models were utilized to estimate the associations of IC deficit scores and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Risk Score
Share to Glaucoma
Share to Glaucoma, Open-Angle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Incidence

Share to Intraocular Pressure

Share to Proportional Hazards Models

Share to UK Biobank

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 42294813
DOI: 10.1167/tvst.15.6.18
PMCID: PMC13277788

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intrinsic Capacity, Polygenic Risk Score, and Risk of Glaucoma.PMID 42294813Read ↗

Step change in glaucoma polygenic risk score performance enables clinical utility and disease prediction across all major ancestriesSemantic proximity Read ↗

Polygenic risk score-based phenome-wide association for glaucoma and its impact on disease susceptibility in two large biobanks.Semantic proximity Read ↗

Recall by polygenic risk score in two biobanks supports a genomic approach for glaucoma detectionSemantic proximity Read ↗

Polygenic Risk Scores Driving Clinical Change in Glaucoma.Semantic proximity Read ↗

Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression.Semantic proximity Read ↗

Integrating Genetics in Glaucoma Screening.Semantic proximity Read ↗

Polygenic risk scores for glaucoma: Impact on diagnosis and disease course.Semantic proximity Read ↗

Association of Monogenic and Polygenic Risk With the Prevalence of Open-Angle Glaucoma.Semantic proximity Read ↗

Genetic Risk Assessment of Degenerative Eye Disease (GRADE): Design of a prospective assessment of polygenic risk scores to predict diagnosis of glaucoma and age-related macular degeneration.Semantic proximity Read ↗

Glaucoma Polygenic Risk Scores Demonstrate Heterogeneous Performance across 2 Large Multiethnic Cohorts.Semantic proximity Read ↗

Multi-trait Polygenic Probability Risk Score Enhances Glaucoma Prediction Across AncestriesSemantic proximity Read ↗

Characteristics of p.Gln368Ter Myocilin Variant and Influence of Polygenic Risk on Glaucoma Penetrance in the UK Biobank.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.