Article
Genomic Features Do Not Account for Differences in Multiple Myeloma Risk by Ancestry.
Blood cancer discovery - 3 Sept 2026
Maclachlan Kylee H, Papadimitriou Marios, Blaney Patrick, Baughn Linda B, Shekarkhand Tala, Poos Alexandra M, Ziccheddu Bachisio, Tang Hongwei, Yan Huihuang, Diamond Benjamin, Zhang Yanming, Cimera Robert, Dogan Ahmet, Gagler Dylan, Boyle Eileen, Hultcrantz Malin, Mailankody Sham, Hassoun Hani, Shah Urvi A, Tan Carlyn, Brown Elizabeth E, Winterkorn Lara, Chu Timothy, Steinsnyder Zoe, Vaksman Zalman, Davies Faith E, Korde Neha, Landgren Ola, Raab Marc S, Lesokhin Alexander M, Robine Nicolas, Weinhold Niels, Usmani Saad Z, Maura Francesco, Morgan Gareth J
Abstract excerpt
Studies have reported conflicting findings regarding the contribution of germline variants or somatic genomic drivers to racial disparities in multiple myeloma. To comprehensively investigate somatic drivers in relation to inherited genetics in multiple myeloma, we combined newly sequenced whole-genome sequencing data with publicly available datasets (total n = 1,286). Overall, we did not identify germline or...
Read the complete abstract on PubMedTopics
- Humans
- Multiple Myeloma
- Genomics