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FaMMily Affairs: Dissecting inherited contributions to multiple myeloma risk.

Seminars in hematology - 1 Feb 2025

Bodnar Saoirse, Brander Tehilla, Gold Julie, Iverson Ayuko, Lagana Alessandro, Onel Kenan, Jagannath Sundar, Parekh Samir, Thibaud Santiago

Abstract excerpt

Etiological links to multiple myeloma (MM) remain poorly understood, though emerging evidence suggests a significant hereditary component. This review integrates current literature on inherited factors contributing to MM risk, synthesizing both epidemiologic and genomic data. We examine familial clustering patterns, assess genome-wide association studies (GWAS) that reveal common genetic variants linked to MM,...

Topics

Humans
Multiple Myeloma
Genetic Predisposition to Disease
Genome-Wide Association Study
Risk Factors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39721861
DOI: 10.1053/j.seminhematol.2024.11.006
PMCID: PMC12008747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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