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Differences in genomic abnormalities among African individuals with monoclonal gammopathies using calculated ancestry

9 Oct 2018

Abstract excerpt

Multiple myeloma (MM) is two- to three-fold more common in African Americans (AAs) compared to European Americans (EAs). This striking disparity, one of the highest of any cancer, may be due to underlying genetic predisposition between these groups. There are multiple unique cytogenetic subtypes of MM, and it is likely that the disparity is associated with only certain subtypes. Previous efforts to understand...

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PMID: 30305608
DOI: 10.1038/s41408-018-0132-1

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