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Article

Genome-Wide and Locus-Level Analyses Reveal Modest, Heterogeneous Genetic Sharing Between Alzheimer's Disease and Myasthenia Gravis.

International journal of molecular sciences - 26 May 2026

Adewuyi Emmanuel O, Auta Asa, Ossai Chinedu I, Anyaegbu Chidozie C, Nguyen Thi Thu Huong, Rahman Md Rezanur, Stephan Blossom C M, Tessema Gizachew A, Nyholt Dale R, Pereira Gavin

Abstract excerpt

Alzheimer's disease (AD) is a neurodegenerative disorder, whereas myasthenia gravis (MG) is an autoimmune neuromuscular disease. Despite their distinct clinical manifestations, both disorders involve immune dysregulation and cholinergic dysfunction, and epidemiological evidence for an association remains inconclusive. Here, we investigated the genetic architecture underlying the AD-MG relationship using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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PMID: 42278322
DOI: 10.3390/ijms27114792
PMCID: PMC13256370

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