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Genetic and mechanistic overlap between Alzheimer’s disease and myasthenia gravis: insights into neuro-immune crosstalk

2025-11-12

Abstract excerpt

<title>Abstract</title> <p> Alzheimer’s disease (AD) and myasthenia gravis (MG) are characterised by acetylcholine dysregulation, yet their epidemiological links remain inconclusive. We comprehensively assessed the genetic relationship between AD and MG, including early- and late-onset MG, using large-scale genome-wide association study data. We detected significant global genetic correlations between AD and MG,...

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Literature Corpus work
65261c6e-525b-5661-923a-c16918242932
DOI
10.21203/rs.3.rs-8080408/v1
Open publication

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