Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide association study of never-smoking non-drinking young adults developing oral squamous cell carcinoma.

BMC cancer - 12 Jun 2026

Cardin Guillaume B, Pellerin-Viger Alicia, Bernard Monique, Kessai Fiona, Ayad Tareck, Bissada Eric, Guertin Louis, Tabet Paul, Gologan Olguta-Ecaterina, Filion Edith, Nguyen-Tan Phuc Felix, Desilets Antoine, Cheng Alexandre Pellan, Rodier Francis, Bahig Houda, Christopoulos Apostolos

Abstract excerpt

BACKGROUND: Germline risk variants for oral squamous cell carcinoma (OSCC) in never-smoking non-drinking (NSND) young adults (YA) are poorly characterized and genome-wide association studies focusing on NSND YA OSCC are lacking. This study aims to evaluate if rare germline variants are associated with NSND YA OSCC. METHODS: We conducted a retrospective, single-center Canadian cohort study of patients who...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Canada
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Risk Score

Share to Genome-Wide Association Study

Share to Germ-Line Mutation

Share to Mouth Neoplasms

Share to Risk Factors

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 42277742
DOI: 10.1186/s12885-026-16342-2
PMCID: PMC13483735

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association study of never-smoking non-drinking young adults developing oral squamous cell carcinoma.PMID 42277742Read ↗

Genomic Signature of Oral Squamous Cell Carcinomas from Non-Smoking Non-Drinking PatientsSemantic proximity Read ↗

The mutational landscape of early- and typical-onset oral tongue squamous cell carcinoma.Semantic proximity Read ↗

A Genome-Wide Association Study Identifies Two Novel Susceptible Regions for Squamous Cell Carcinoma of the Head and Neck.Semantic proximity Read ↗

Comprehensive review of genetic factors contributing to head and neck squamous cell carcinoma development in low-risk, nontraditional patients.Semantic proximity Read ↗

Polygenic risk score-based phenome-wide association study of head and neck cancer across two large biobanks.Semantic proximity Read ↗

Interactive effects of CDKN2B-AS1 gene polymorphism and habitual risk factors on oral cancer.Semantic proximity Read ↗

Cross-ancestral GWAS identifies 29 novel variants across Head and Neck Cancer subsitesSemantic proximity Read ↗

Germline variants in DNA repair genes are associated with young-onset head and neck cancer.Semantic proximity Read ↗

Genetic and Molecular Differences in Head and Neck Cancer Based on Smoking History.Semantic proximity Read ↗

Oral squamous cell carcinoma risk and magnitude of association in inherited cancer predisposition syndromes: evidence from a large real-world cohort.Semantic proximity Read ↗

Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers.Semantic proximity Read ↗

Copy number variation: A prognostic marker for young patients with squamous cell carcinoma of the oral tongueSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.