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Article

Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2014

Pickering Curtis R, Zhang Jiexin, Neskey David M, Zhao Mei, Jasser Samar A, Wang Jiping, Ward Alexandra, Tsai C Jillian, Ortega Alves Marcus V, Zhou Jane H, Drummond Jennifer, El-Naggar Adel K, Gibbs Richard, Weinstein John N, Wheeler David A, Wang Jing, Frederick Mitchell J, Myers Jeffrey N

Abstract excerpt

PURPOSE: Epidemiologic studies have identified an increasing incidence of squamous cell carcinoma of the oral tongue (SCCOT) in younger patients. EXPERIMENTAL DESIGN: DNA isolated from tongue tumors of young (<45 years, non-smokers) and old (>45 years) patients at was subjected to whole-exome sequencing and copy-number analysis. These data were compared with data from similar patients in the TCGA (The Cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24874835
DOI: 10.1158/1078-0432.CCR-14-0565
PMCID: PMC4102633

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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