Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic determinants involved in the susceptibility of Pseudomonas aeruginosa to beta-lactam antibiotics.

Antimicrobial agents and chemotherapy - 1 Oct 2010

Alvarez-Ortega Carolina, Wiegand Irith, Olivares Jorge, Hancock Robert E W, Martínez José Luis

Abstract excerpt

The resistome of P. aeruginosa for three β-lactam antibiotics, namely, ceftazidime, imipenem, and meropenem, was deciphered by screening a comprehensive PA14 mutant library for mutants with increased or reduced susceptibility to these antimicrobials. Confirmation of the phenotypes of all selected mutants was performed by Etest. Of the total of 78 confirmed mutants, 41 demonstrated a reduced susceptibility...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to beta-Lactamases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to beta-Lactams

Share to Genetic Complementation Test

Share to Microbial Sensitivity Tests

Share to Pseudomonas aeruginosa

Share to Serine Endopeptidases

Share to Sigma Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 20679510
DOI: 10.1128/AAC.00257-10
PMCID: PMC2944606

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic determinants involved in the susceptibility of Pseudomonas aeruginosa to beta-lactam antibiotics.PMID 20679510Read ↗

Complex ciprofloxacin resistome revealed by screening a Pseudomonas aeruginosa mutant library for altered susceptibility.Semantic proximity Read ↗

Characterization of the polymyxin B resistome of Pseudomonas aeruginosa.Semantic proximity Read ↗

Correlation between phenotypic antibiotic susceptibility and the resistome in Pseudomonas aeruginosa.Semantic proximity Read ↗

Pseudomonas aeruginosa ceftolozane-tazobactam resistance development requires multiple mutations leading to overexpression and structural modification of AmpC.Semantic proximity Read ↗

Genomewide identification of genetic determinants of antimicrobial drug resistance in Pseudomonas aeruginosa.Semantic proximity Read ↗

Pseudomonas aeruginosa: all roads lead to resistance.Semantic proximity Read ↗

The neglected intrinsic resistome of bacterial pathogens.Semantic proximity Read ↗

Ceftazidime resistance in Pseudomonas aeruginosa is multigenic and complexSemantic proximity Read ↗

Whole-Genome Sequencing of Resistance, Virulence and Regulation Genes in Extremely Resistant Strains of Pseudomonas aeruginosa.Semantic proximity Read ↗

Multi-omics profiling of cross-resistance between ceftazidime-avibactam and meropenem identifies common and strain-specific mechanisms in <i>Pseudomonas aeruginosa</i> clinical isolatesSemantic proximity Read ↗

The Pseudomonas aeruginosa Resistome: Permanent and Transient Antibiotic Resistance, an Overview.Semantic proximity Read ↗

Keeping up with the pathogens: improved antimicrobial resistance detection and prediction from Pseudomonas aeruginosa genomes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.