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The Use of Single-Cell Mitochondrial DNA SNP Combinations for Distinguishing Organ-Specific Cell Types.

Cells - 21 May 2026

Wang Shuai, Tu Xinyue, Zhu Haozhe, Gao Ce, Gao Jianan, Wei Jinsong, Shi Hui, Peng Jinrong

Abstract excerpt

Cell lineage relationship studies in developmental and regenerative biology have been greatly advanced using techniques such as fluorescent labeling driven by cell-type-specific promoters. Nevertheless, unbiased non-invasive tools for distinguishing cell lineages are inevitably desired. Mitochondrial DNA (mtDNA) exhibits wide-range single-nucleotide polymorphisms (SNPs) among individual cells. Here, we aim to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42193956
DOI: 10.3390/cells15100947
PMCID: PMC13205045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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