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Cellular and molecular basis of liver regeneration

22 Jan 2020

Abstract excerpt

Recent advances in genetics and genomics have reinvigorated the field of liver regeneration. It is now possible to combine lineage-tracing with genome-wide studies to genetically mark individual liver cells and their progenies and detect precise changes in their genome, transcriptome, and proteome under normal versus regenerative settings. The recent use of single-cell RNA sequencing methodologies in model...

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PMID: 31980376
DOI: 10.1016/j.semcdb.2019.12.004

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