Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolution of animal Piwi-interacting RNAs and prokaryotic CRISPRs.

Briefings in functional genomics - 1 Jul 2012

Kumar M Senthil, Chen Kevin C

Abstract excerpt

Piwi-interacting RNAs (piRNAs) and CRISPR RNAs (crRNAs) are two recently discovered classes of small noncoding RNA that are found in animals and prokaryotes, respectively. Both of these novel RNA species function as components of adaptive immune systems that protect their hosts from foreign nucleic acids-piRNAs repress transposable elements in animal germlines, whereas crRNAs protect their bacterial hosts from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Databases, Genetic
Share to Immune System

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Models, Theoretical

Share to Nucleic Acids

Share to Prokaryotic Cells

Share to RNA, Small Interfering

Source

Open in PubMed Open full text

Identifiers

PMID: 22539610
DOI: 10.1093/bfgp/els016
PMCID: PMC3398257

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evolution of animal Piwi-interacting RNAs and prokaryotic CRISPRs.PMID 22539610Read ↗

CRISPR/Cas, the immune system of bacteria and archaea.Semantic proximity Read ↗

Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines.Semantic proximity Read ↗

Diversity, evolution, and therapeutic applications of small RNAs in prokaryotic and eukaryotic immune systems.Semantic proximity Read ↗

Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elementsSemantic proximity Read ↗

PIWI proteins and PIWI-interacting RNAs in the soma.Semantic proximity Read ↗

piRNAs derived from ancient viral processed pseudogenes as transgenerational sequence-specific immune memory in mammalsSemantic proximity Read ↗

Function, targets, and evolution of Caenorhabditis elegans piRNAs.Semantic proximity Read ↗

Conserved and ubiquitous expression of piRNAs and PIWI genes in mollusks antedates the origin of somatic PIWI/piRNA expression to the root of bilateriansSemantic proximity Read ↗

Evolutionary and mechanistic diversity of Type I-F CRISPR-associated transposons.Semantic proximity Read ↗

Rapid repetitive element-mediated expansion of piRNA clusters in mammalian evolution.Semantic proximity Read ↗

A Single Mechanism of Biogenesis, Initiated and Directed by PIWI Proteins, Explains piRNA Production in Most AnimalsSemantic proximity Read ↗

Zili is required for germ cell differentiation and meiosis in zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.