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Article

Association of CD32-131H>R Polymorphism with End-Stage Chronic Obstructive Pulmonary Disease and Interstitial Lung Diseases.

Journal of innate immunity - 1 Jan 2026

Berger Sarah M, Kühner Laura M, Schwarzinger Ines M, Heiss Spornberger Verena, Jaksch Peter, Puchhammer-Stöckl Elisabeth, Vietzen Hannes

Abstract excerpt

INTRODUCTION: Progression to end-stage lung diseases is influenced by both environmental and genetic factors, yet predictive markers remain limited. The CD32-131H>R polymorphism in the FCGR2A gene alters the affinity of the FcγRIIa receptor for IgG and may impair immune clearance, potentially influencing immune responses involved in chronic lung disease. In our study, we investigated the association between the...

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Source

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Identifiers

PMID: 42184229
DOI: 10.1159/000552727
PMCID: PMC13391064

Genes

FCGR2A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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