Article
Bilirubin-associated single nucleotide polymorphism (SNP) and respiratory health outcomes: a mendelian randomization study.
Respiratory research - 20 Jul 2023
Baldomero Arianne K, MacDonald David M, Kaplan Adam, Lock Eric, Cho Michael H, Bowler Russell, Gillenwater Lucas, Kunisaki Ken M, Wendt Chris H
Abstract excerpt
BACKGROUND: Observational studies have shown an association between higher bilirubin levels and improved respiratory health outcomes. Targeting higher bilirubin levels has been proposed as a novel therapeutic strategy in COPD. However, bilirubin levels are influenced by multiple intrinsic and extrinsic factors, and these observational studies are prone to confounding. Genetic analyses are one approach to...
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