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Article

Early atherosclerosis and IgG2 to bacteria are associated with FcgammaRIIa genotype in non-smokers.

European journal of clinical investigation - 1 Jun 2009

Sämpi M, Ukkola O, Päivänsalo M, Kesäniemi Y A, Hörkkö S

Abstract excerpt

BACKGROUND: Involvement of low density lipoprotein (LDL) immune complexes (ICs) in atherogenesis has been proposed. Human FcgammaRIIa receptor (CD32) plays a crucial role in the phagocytosis of IgG(2) ICs and a functional point mutation 131His/Arg diminishes IgG(2) binding to the receptor. STUDY DESIGN: We examined FcgammaRIIa-131His/Arg polymorphism, IgG(2) antibody titres to oxidized low-density lipoprotein...

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Share to Atherosclerosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Immunoglobulin G

Share to Lipoproteins, LDL

Share to Pneumococcal Infections

Share to Polymorphism, Genetic

Share to Receptors, IgG

Source

Identifiers

PMID: 19490059
DOI: 10.1111/j.1365-2362.2009.02138.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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