Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease.

doi:10.1164/rccm.201302-0247OC

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Article

Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease.

American journal of respiratory and critical care medicine - 15 Oct 2013

Cheng Donavan T, Kim Deog Kyeom, Cockayne Debra A, Belousov Anton, Bitter Hans, Cho Michael H, Duvoix Annelyse, Edwards Lisa D, Lomas David A, Miller Bruce E, Reynaert Niki, Tal-Singer Ruth, Wouters Emiel F M, Agustí Alvar, Fabbri Leonardo M, Rames Alex, Visvanathan Sudha, Rennard Stephen I, Jones Paul, Parmar Harsukh, MacNee William, Wolff Gerhard, Silverman Edwin K, Mayer Ruth J, Pillai Sreekumar G

Abstract excerpt

RATIONALE: Emphysema in chronic obstructive pulmonary disease (COPD) can be characterized by high-resolution chest computed tomography (HRCT); however, the repeated use of HRCT is limited because of concerns regarding radiation exposure and cost. OBJECTIVES: To evaluate biomarkers associated with emphysema and COPD-related clinical characteristics, and to assess the relationships of soluble receptor for advanced...

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PMID: 23947473
DOI: 10.1164/rccm.201302-0247OC

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AGER

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