Article
Association of FcγRIIa R131H polymorphism with idiopathic pulmonary fibrosis severity and progression.
BMC pulmonary medicine - 7 Oct 2010
Bournazos Stylianos, Grinfeld Jacob, Alexander Karen M, Murchison John T, Wallace William A, McFarlane Pauline, Hirani Nikhil, Simpson A John, Dransfield Ian, Hart Simon P
Abstract excerpt
BACKGROUND: A significant genetic component has been described for idiopathic pulmonary fibrosis (IPF). The R131H (rs1801274) polymorphism of the IgG receptor FcγRIIa determines receptor affinity for IgG subclasses and is associated with several chronic inflammatory diseases. We investigated whet...
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