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Article

CYP gene variants show preliminary evidence of association with patient-reported outcomes in active-duty service members with chronic pain.

Molecular pain - 1 Jan 2026

Tintle Nathan L, Ryder Nathan A, Westra Jason, Wi Dahee, Shimada Sotaro, Ieronimakis Nicholas, McQuinn Honor M, Snow Tyler J, Doorenbos Ardith Z, Flynn Diane M

Abstract excerpt

Chronic pain is highly prevalent among active-duty service members (ADSMs) and contributes to substantial physical, psychological, and social burden. Genetic factors are recognized as central to pain susceptibility and treatment response. While few studies have examined the genes involved in cortisol synthesis, changes in the coding of cytochrome P450 (CYP) enzymes responsible for cortisol production have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42175782
DOI: 10.1177/17448069261454823
PMCID: PMC13276232

Genes

CYP11B1
CYP17A1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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