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Article

Sex Bias and Genotype Influence on Opioid Safety Profile in Chronic Low Back Pain.

The Clinical journal of pain - 1 Jun 2020

Margarit César, Roca Reyes, Inda María-Del-Mar, Muriel Javier, Ballester Pura, Flor Andrea, Morales Domingo, Peiró Ana M

Abstract excerpt

OBJECTIVES: The use of opioids to relieve pain is a challenge because of the high variability in dose requirements and tolerance profiles. Among potential modulators are the individual's genetic background and being female. Our aim was to evaluate sex bias and genotype-related influence on opioid titration safety, in chronic low back pain (CLBP), the most frequent chronic noncancer pain. METHODS: A 3-year...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32149782
DOI: 10.1097/AJP.0000000000000824

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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