Article
Three major haplotypes of the beta2 adrenergic receptor define psychological profile, blood pressure, and the risk for development of a common musculoskeletal pain disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2006
Diatchenko Luda, Anderson Amy D, Slade Gary D, Fillingim Roger B, Shabalina Svetlana A, Higgins Tomas J, Sama Swetha, Belfer Inna, Goldman David, Max Mitchell B, Weir Bruce S, Maixner William
Abstract excerpt
Adrenergic receptor beta(2) (ADRB2) is a primary target for epinephrine. It plays a critical role in mediating physiological and psychological responses to environmental stressors. Thus, functional genetic variants of ADRB2 will be associated with a complex array of psychological and physiological phenotypes. These genetic variants should also interact with environmental factors such as physical or emotional...
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