Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fibroblast-like cells accumulate late in human coronary atherosclerosis contributing to necrotic core formation.

Cardiovascular research - 26 Mar 2026

Morales-Cano Daniel, Sharysh Diana, Albarrán-Juárez Julián, de Molina Antonio, Labrador-Cantarero Verónica, Møller Cecilie Markvard, Carramolino Laura, Bentzon Jacob F

Abstract excerpt

AIMS: Proliferation of arterial smooth muscle cells (SMCs) and their modulation to alternative mesenchymal phenotypes is central to atherosclerotic lesion growth. It has been studied extensively in mouse models, but a detailed analysis of when and where different mesenchymal cell types accumulate in human atherosclerosis is lacking. This study mapped mesenchymal cell populations during the progression of human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autopsy
Share to Carotid Artery Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Vessels

Share to Fibrosis

Share to Myocytes, Smooth Muscle

Share to Necrosis

Share to Osteoprotegerin

Share to Plaque, Atherosclerotic

Source

Open in PubMed Open full text

Identifiers

PMID: 41553378
DOI: 10.1093/cvr/cvag002
PMCID: PMC13019684

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fibroblast-like cells accumulate late in human coronary atherosclerosis contributing to necrotic core formation.PMID 41553378Read ↗

Modulated smooth muscle cells accumulate late in human coronary atherosclerosis and are temporally and spatially linked to necrotic core formationSemantic proximity Read ↗

Mouse, pig, and human atherosclerotic lesions have common and distinct mesenchymal cell populationsSemantic proximity Read ↗

Mouse, Pig, and Human Atherosclerotic Lesions Have Common and Distinct Mesenchymal Cell Populations.Semantic proximity Read ↗

Single cell spatial transcriptomics integration deciphers the morphological heterogeneity of atherosclerotic carotid arteriesSemantic proximity Read ↗

High-Dimensional Single-Cell Multimodal Landscape of Human Carotid AtherosclerosisSemantic proximity Read ↗

A rare pre-existing progenitor-like Primed SMC compartment is the dominant inferred source of SMC-derived cellularity in vascular injury and atherosclerosisSemantic proximity Read ↗

Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.Semantic proximity Read ↗

Molecular and spatiotemporal characterization of cells in murine atherosclerotic plaquesSemantic proximity Read ↗

Fibroblasts in atherosclerosis: heterogeneous and plastic participantsSemantic proximity Read ↗

Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instabilitySemantic proximity Read ↗

Vascular smooth muscle cells in atherosclerosis: time for a re-assessment.Semantic proximity Read ↗

Single-Cell Multimodal Profiling Reveals a Novel CD26+ Fibroblast Subpopulation in Atherosclerosis-Brief Report.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.