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Article

Multiple sclerosis genetics.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Jan 2018

Canto Ester, Oksenberg Jorge R

Abstract excerpt

A broad scientific consensus has emerged linking multiple sclerosis (MS) risk to multiple independent and interacting DNA variants that are relatively frequent in the population and act in concert with environmental exposures. The multifactorial, polygenic model of heritability provided the rationale and impetus to pursue genome-wide association studies (GWAS), which have been highly successful in uncovering...

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PMID: 29307290
DOI: 10.1177/1352458517737371

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Source receipt: pubmed, retrieved 7 Sept 2026.

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