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Article

A Deep Dive into the Molecular and Immune Landscape of Undifferentiated Carcinomas with Osteoclast-like Giant Cells.

Cells - 2 May 2026

Chang Eric, Shi Jiaqi

Abstract excerpt

Undifferentiated carcinoma with osteoclast-like giant cells (UCOGC) is a rare, distinct subtype of pancreatic carcinoma, formally classified separately from undifferentiated carcinoma (UC) of the pancreas in the World Health Organization's 2010 and 2019 revisions. Whereas classic UC is associated with a poor prognosis and low survival rates, recent studies suggest that patients with UCOGC experience significantly...

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Source

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Identifiers

PMID: 42121938
DOI: 10.3390/cells15090837
PMCID: PMC13162917

Genes

CDKN2A
KRAS
SMAD4
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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A Deep Dive into the Molecular and Immune Landscape of Undifferentiated Carcinomas with Osteoclast-like Giant Cells.PMID 42121938Read ↗

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