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Article

Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas harboring KRAS and BRCA mutations: case report and whole exome sequencing analysis.

BMC gastroenterology - 26 Jun 2020

Yang Guangjian, Yin Jiangxia, Ou Kai, Du Qiang, Ren Wenhao, Jin Yujing, Peng Liming, Yang Lin

Abstract excerpt

BACKGROUND: Undifferentiated carcinoma with osteoclast-like giant cells (UC-OGC) is an extremely uncommon pancreatic neoplasm that comprises less than 1% of all exocrine pancreatic tumors. To date, cases and data from whole-exome sequencing (WES) analysis have been reported by specific studies. We report a case of pancreatic UC-OGC with a literature review, and provide novel insights into the molecular...

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Identifiers

PMID: 32590950
DOI: 10.1186/s12876-020-01351-7
PMCID: PMC7318525

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