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Article

Integrin-focal adhesion-cytoskeleton signaling axis variations and genetic susceptibility to SCD-CAD.

Forensic science international - 1 Sept 2026

Cai Mengqi, He Yan, Meng Haoliang, Luo Bin, Gao Yuzhen

Abstract excerpt

Sudden cardiac death (SCD) is a leading cause of global mortality, with coronary artery disease (CAD) being the primary etiology. Vascular smooth muscle cell (VSMC) migration and proliferation, regulated by actin cytoskeletal dynamics, are pivotal to CAD pathogenesis. The integrin-focal adhesion-cytoskeleton signaling axis modulates these processes; however, its genetic contribution to SCD-CAD remains poorly...

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Share to Coronary Artery Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Electrophoresis, Capillary

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Source

Identifiers

PMID: 42114173
DOI: 10.1016/j.forsciint.2026.112999

Genes

CAD
SCD
BCAR1
CRK
DOCK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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