Novel loci associated with increased risk of sudden cardiac death in the context of coronary artery disease.

doi:10.1371/journal.pone.0059905

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Article

Novel loci associated with increased risk of sudden cardiac death in the context of coronary artery disease.

PloS one - 1 Jan 2013

Huertas-Vazquez Adriana, Nelson Christopher P, Guo Xiuqing, Reinier Kyndaron, Uy-Evanado Audrey, Teodorescu Carmen, Ayala Jo, Jerger Katherine, Chugh Harpriya, Braund Peter S, Deloukas Panos, Hall Alistair S, Balmforth Anthony J, Jones Michelle, Taylor Kent D, Pulit Sara L, Newton-Cheh Christopher, Gunson Karen, Jui Jonathan, Rotter Jerome I, Albert Christine M, Samani Nilesh J, Chugh Sumeet S

Abstract excerpt

BACKGROUND: Recent genome-wide association studies (GWAS) have identified novel loci associated with sudden cardiac death (SCD). Despite this progress, identified DNA variants account for a relatively small portion of overall SCD risk, suggesting that additional loci contributing to SCD susceptibility await discovery. The objective of this study was to identify novel DNA variation associated with SCD in the...

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PMID: 23593153
DOI: 10.1371/journal.pone.0059905
PMCID: PMC3617189

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