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Article

Genetic Association of Circulating Proteins and Gene Transcripts With Spontaneous Coronary Artery Dissection.

Circulation. Genomic and precision medicine - 1 Feb 2026

Ardissino Maddalena, Morley Alec P, Truong Buu, Schuermans Art, Reddy Rohin K, Milani Martina, Sacco Alice, Ware James S, Burgess Stephen, Halliday Brian P, Cao Thong Huy, Quinn Paulene A, Ng Leong L, Baranowska-Clarke Ania A, Natarajan Pradeep, Butterworth Adam S, Honigberg Michael C, Nicolaides Kypros, Webb Thomas, Adlam David, de Marvao Antonio

Abstract excerpt

BACKGROUND: Spontaneous coronary artery dissection (SCAD) is an uncommon cause of myocardial infarction that disproportionately affects women, particularly during pregnancy and the peripartum period. Limited understanding of its underlying pathophysiology hinders the development of effective preventive and therapeutic strategies. METHODS: This study investigated associations between genetically predicted...

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Source

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Identifiers

PMID: 41608794
DOI: 10.1161/CIRCGEN.125.005330
PMCID: PMC12915550

Genes

ECM1
AFAP1
SPON1
STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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