Article
Mining the genome for susceptibility to diabetic nephropathy: the role of large-scale studies and consortia.
Seminars in nephrology - 1 Mar 2007
Iyengar Sudha K, Freedman Barry I, Sedor John R
Abstract excerpt
Approximately 30% of individuals with type 1 and type 2 diabetes develop persistent albuminuria, lose renal function, and are at increased risk for cardiovascular and other microvascular complications. Diabetes and kidney diseases rank within the top 10 causes of death in Westernized countries and cause significant morbidity. Given these observations, genetic, genomic, and proteomic investigations have been...
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