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Article

Mutations in CHIP-associated genes at myeloid neoplasm diagnosis and risk of cardiovascular/cerebrovascular events.

Annals of medicine - 1 Dec 2026

Wang Yao, Zhao Dewan, Chen Yulong, Xu He, Song Guirong, Sun Xiuli

Abstract excerpt

BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP)-associated somatic mutations are associated with increased cardiovascular and cerebrovascular risk in the general population; whether mutations detected at myeloid neoplasm (MN) diagnosis predict incident cardiovascular and cerebrovascular events (CCVEs) is unclear. METHODS: We retrospectively studied 203 adults with newly diagnosed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42037246
DOI: 10.1080/07853890.2026.2663092
PMCID: PMC13123072

Genes

ASXL1
DNMT3A
TET2
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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