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Article

Pathway-Specific Polygenic Risk Scores and Cardiorenal Complications in Asians With Type 2 Diabetes.

Diabetes, obesity & metabolism - 1 Jun 2026

Gurung Resham L, Zheng Huili, Tan Jia Le Ivan, Liu Sylvia, Liu Jian-Jun, Ang Keven, Subramaniam Tavintharan, Sum Chee Fang, Lim Su Chi

Abstract excerpt

AIM: Risk of cardiorenal complications varies among patients with type 2 diabetes (T2D). T2D pathway-specific polygenic risk scores (psPRS) capture genetic susceptibility related to distinct intermediate biological processes associated with T2D and cardiorenal outcomes, predominantly in European populations. Their relevance in multi-ethnic Asian populations remains unclear. We explored associations between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41949066
DOI: 10.1111/dom.70741

Genes

EDA2R
FABP4
LILRA5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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