Article

Prediction of Cardiovascular and Renal Complications of Diabetes by a multi-Polygenic Risk Score in Different Ethnic Groups

2025-06-18

Abstract excerpt

We developed a multi-Polygenic risk score (multiPRS) to predict the risk of nephropathy, stroke, and myocardial infarction in people with type 2 diabetes of European descent. The underrepresentation of non-European populations remains a major challenge in genomics research. <h4>Objective: </h4> To evaluate the ability of our multiPRS model to accurately predict these complications in patients of African and South...

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Literature Corpus work: b4ad5de4-b845-53b9-81ba-1c3b08915770
DOI: 10.1101/2025.06.17.25329804

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