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Towards scalable biomarker discovery in posttraumatic stress disorder: triangulating genomic and phenotypic evidence from a health system biobank.

Molecular psychiatry - 1 Aug 2026

Lee Younga Heather, Zhang Yingzhe, Espinosa Dice Ana Lucia, Li Josephine H, Tubbs Justin D, Feng Yen-Chen Anne, Ge Tian, Maihofer Adam X, Nievergelt Caroline M, Smoller Jordan W, Koenen Karestan C, Roberts Andrea L, Slopen Natalie

Abstract excerpt

Biomarkers can potentially improve the diagnosis, monitoring, and treatment of posttraumatic stress disorder (PTSD). However, PTSD biomarkers that are scalable and easily integrated into real-world clinical settings have not been identified. The analysis was conducted between June to November 2024 using genomic samples and laboratory test results recorded in the Mass General Brigham (MGB) Health System. The...

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PMID: 41946832
DOI: 10.1038/s41380-026-03553-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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