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Distinguishing vulnerability and resilience to posttraumatic stress disorder evaluating traumatic experiences, genetic risk and electronic health records.

Psychiatry research - 1 Jul 2024

Løkhammer Solveig, Koller Dora, Wendt Frank R, Choi Karmel W, He Jun, Friligkou Eleni, Overstreet Cassie, Gelernter Joel, Hellard Stéphanie Le, Polimanti Renato

Abstract excerpt

What distinguishes vulnerability and resilience to posttraumatic stress disorder (PTSD) remains unclear. Levering traumatic experiences reporting, genetic data, and electronic health records (EHR), we investigated and predicted the clinical comorbidities (co-phenome) of PTSD vulnerability and resilience in the UK Biobank (UKB) and All of Us Research Program (AoU), respectively. In 60,354 trauma-exposed UKB...

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Comorbidity
Electronic Health Records
Genome-Wide Association Study
Multifactorial Inheritance
Resilience, Psychological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sleep Wake Disorders

Stress Disorders, Post-Traumatic

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PMID: 38744179
DOI: 10.1016/j.psychres.2024.115950
PMCID: PMC11156529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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