Back to search

Article

A Blood-Based Transcriptomic Signature for PTSD Classification Using Machine Learning

2026-05-13

Abstract excerpt

Post-traumatic stress disorder (PTSD) remains a significant psychiatric burden; despite growing biomarker research, no blood-based molecular diagnostic tool has been clinically validated for routine use. In this study, we developed a machine learning classifier for PTSD using peripheral blood leukocyte RNA-seq data from combat-exposed U.S. Marines (GSE64813), diagnosed via the Clinician-Administered PTSD Scale (CA...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0a77e84d-d72a-5f5e-8e73-67fa42a160bf
DOI
10.64898/2026.05.10.26352854
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A Blood-Based Transcriptomic Signature for PTSD Classification Using Machine LearningDOI 10.64898/2026.05.10.26352854
Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorderSemantic proximity
Blood-based gene-expression predictors of PTSD risk and resilience among deployed marines: a pilot study.Semantic proximity
PTSD blood transcriptome mega-analysis: Shared inflammatory pathways across biological sex and modes of traumasSemantic proximity
Altered gene expression and PTSD symptom dimensions in World Trade Center respondersSemantic proximity
Analysis of Post-traumatic Stress Disorder Gene Expression Profiles in a Prospective, Community-based CohortSemantic proximity
Gene expression associated with PTSD in World Trade Center responders: An RNA sequencing study.Semantic proximity
Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits.Semantic proximity
Mapping the transcriptomics landscape of post-traumatic stress disorder symptom dimensions in World Trade Center respondersSemantic proximity
Transcriptomic Organization of Human Posttraumatic Stress DisorderSemantic proximity
Genome-wide association study of posttraumatic stress disorder in a cohort of Iraq-Afghanistan era veterans.Semantic proximity
Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene.Semantic proximity
Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker developmentSemantic proximity
Select a neighboring publication to make it the new centre.