Article
Gene expression associated with PTSD in World Trade Center responders: An RNA sequencing study.
Translational psychiatry - 18 Dec 2017
Kuan Pei-Fen, Waszczuk Monika A, Kotov Roman, Clouston Sean, Yang Xiaohua, Singh Prashant K, Glenn Sean T, Cortes Gomez Eduardo, Wang Jianmin, Bromet Evelyn, Luft Benjamin J
Abstract excerpt
The gene expression approach has provided promising insights into the pathophysiology of posttraumatic stress disorder (PTSD). However, few studies used hypothesis-free transcriptome-wide approach to comprehensively understand gene expression underpinning PTSD. A transcriptome-wide expression study using RNA sequencing of whole blood was conducted in 324 World Trade Center responders (201 with never, 81 current,...
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