Article
Genomic Approaches to Posttraumatic Stress Disorder: The Psychiatric Genomic Consortium Initiative.
Biological psychiatry - 15 May 2018
Nievergelt Caroline M, Ashley-Koch Allison E, Dalvie Shareefa, Hauser Michael A, Morey Rajendra A, Smith Alicia K, Uddin Monica
Abstract excerpt
Posttraumatic stress disorder (PTSD) after exposure to a traumatic event is a highly prevalent psychiatric disorder. Heritability estimates from twin studies as well as from recent molecular data (single nucleotide polymorphism-based heritability) indicate moderate to high heritability, yet robust genetic variants for PTSD have not yet been identified and the genetic architecture of this polygenic disorder...
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