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Article

Bridging the gap between tumor evolution and clonality diagnostics in multiple lung carcinomas.

Seminars in cancer biology - 1 May 2026

Janssen Jurriaan, Allgäuer Michael, Ylstra Bauke, Draijer Swip, Kim Yongsoo, Budczies Jan, Kazdal Daniel, Stenzinger Albrecht, Kirchner Martina, Radonic Teodora

Abstract excerpt

Differentiating multiple primary lung carcinomas (MPLCs) from intrapulmonary metastases (IPMs) remains a critical challenge in the management of patients with multiple non-small cell lung carcinomas (NSCLCs). Although the clinical presentation of MPLCs and IPMs often appears similar, they represent biologically distinct evolutionary processes. In the genomics era, molecular pathology has provided new tools to...

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Identifiers

PMID: 41912125
DOI: 10.1016/j.semcancer.2026.03.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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